1. Chen MC, Chen CH, Chuang HC, Kulp SK, Teng CM,
Chen CS. Novel mechanism by which histone deacetylase inhibitors facilitate
topoisomerase IIα degradation in hepatocellular carcinoma cells. Hepatology. 2011 Jan;53(1):148-59.
2. Chen MC, Pan SL, Shi Q, Xiao Z, Lee KH, Li TK, Teng CM. QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells. Cancer Sci. 2012 Jan;103(1):80-7.
3. Chen CH, Huang PH, Chu PC, Chen MC, Chou CC, Wang D, Kulp SK, Teng CM, Wang Q, Chen CS. Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression. J Biol Chem. 2011 Mar 25;286(12):9968-76.
4. Lai CY, Tsai AC, Chen MC, Chang LH, Sun HL, Chang YL, Chen CC, Teng CM, Pan SL. Aciculatin Induces p53-Dependent Apoptosis via MDM2 Depletion in Human Cancer Cells In Vitro and In Vivo. PLoS One. 2012;7(8):e42192.
5. Chen MC, Chen CH, Liu YN, Wang HP, Pan SL, and Teng CM. TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells. Cancer Lett. 2013 Aug 19;336(2):370-8.
6. Chen MC, Chen CH, Wang JC, Tsai AC, Liou JP, Pan SL, and Teng CM. Synergistic effect of erlotinib in combination with HDAC inhibitor MPT0E028 against human NSCLC cells. Cell Death Dis. 2013 Sep 19;4:e810.
7. Chen CH, Chen MC, Tsai AC, Wang JC, Liou JP, Pan SL, and Teng CM. Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in hepatocellular carcinoma cells in vitro and in vivo. Clin Cancer Res. 2014 Mar 1;20(5):1274-87.
8. Lee HY, Tsai AC, Chen MC, Shen PJ, Cheng YC, Kuo CC, Pan SL, Liu YM, Liu JF, Yeh TK, Wang JC, Chang CY, Chang JY, Liou JP. Azaindolylsulfonamides, a More Selective Inhibitory Effect on Histone 6 Activity, Exhibit Antitumor Activity in Colorectal Cancer HCT116 Cells. J Med Chem. 2014 May 22;57(10):4009-22.
9. Mehndiratta S, Chiang YF, Lai MJ, Lee HY, Chen MC, Kuo CC, Chang CY, Chang JY, Liou JP. Concise synthesis of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents. Bioorg Med Chem. 2014 Sep 1;22(17):4917-23.
10. Wu SY, Pan SL, Xiao ZY, Hsu JL, Chen MC, Lee KH, Teng CM. NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells. PLoS One. 2014; 9(11): e112220.
11. Chen MC, Pan SL, Liou JP, and Teng CM. Development of natural-based microtubule-interfering agents for cancer treatment. (preparing and submitting)
12. Chen CH, Chen MC, Wang JC, Liou JP, Pan SL, and Teng CM. The novel HDAC inhibitor, MPT0G028, induces cell death via regulation of b-catenin in human colon cancer HCT116 cells. (preparing and submitting)
13. Chen MC, Zhou B, Zhang K, Yuan YC, Un F, Hu S, Chou CM, Chen CH, Wu J, Wang Y, Liu X, Smith L, Warden CD, Liu Z, Li H, Su L, Malkas LH, Chung YM, Hu MC, Yen Y. The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro. Mol Pharmacol. 2015 Mar 26. pii: mol.114.094987.
2. Chen MC, Pan SL, Shi Q, Xiao Z, Lee KH, Li TK, Teng CM. QS-ZYX-1-61 induces apoptosis through topoisomerase II in human non-small-cell lung cancer A549 cells. Cancer Sci. 2012 Jan;103(1):80-7.
3. Chen CH, Huang PH, Chu PC, Chen MC, Chou CC, Wang D, Kulp SK, Teng CM, Wang Q, Chen CS. Energy restriction-mimetic agents induce apoptosis in prostate cancer cells in part through epigenetic activation of KLF6 tumor suppressor gene expression. J Biol Chem. 2011 Mar 25;286(12):9968-76.
4. Lai CY, Tsai AC, Chen MC, Chang LH, Sun HL, Chang YL, Chen CC, Teng CM, Pan SL. Aciculatin Induces p53-Dependent Apoptosis via MDM2 Depletion in Human Cancer Cells In Vitro and In Vivo. PLoS One. 2012;7(8):e42192.
5. Chen MC, Chen CH, Liu YN, Wang HP, Pan SL, and Teng CM. TW01001, a novel piperazinedione compound, induces mitotic arrest and autophagy in non-small cell lung cancer A549 cells. Cancer Lett. 2013 Aug 19;336(2):370-8.
6. Chen MC, Chen CH, Wang JC, Tsai AC, Liou JP, Pan SL, and Teng CM. Synergistic effect of erlotinib in combination with HDAC inhibitor MPT0E028 against human NSCLC cells. Cell Death Dis. 2013 Sep 19;4:e810.
7. Chen CH, Chen MC, Tsai AC, Wang JC, Liou JP, Pan SL, and Teng CM. Synergistic interaction between the HDAC inhibitor, MPT0E028, and sorafenib in hepatocellular carcinoma cells in vitro and in vivo. Clin Cancer Res. 2014 Mar 1;20(5):1274-87.
8. Lee HY, Tsai AC, Chen MC, Shen PJ, Cheng YC, Kuo CC, Pan SL, Liu YM, Liu JF, Yeh TK, Wang JC, Chang CY, Chang JY, Liou JP. Azaindolylsulfonamides, a More Selective Inhibitory Effect on Histone 6 Activity, Exhibit Antitumor Activity in Colorectal Cancer HCT116 Cells. J Med Chem. 2014 May 22;57(10):4009-22.
9. Mehndiratta S, Chiang YF, Lai MJ, Lee HY, Chen MC, Kuo CC, Chang CY, Chang JY, Liou JP. Concise synthesis of 7-anilino-indoline-N-benzenesulfonamides as antimitotic and vascular disrupting agents. Bioorg Med Chem. 2014 Sep 1;22(17):4917-23.
10. Wu SY, Pan SL, Xiao ZY, Hsu JL, Chen MC, Lee KH, Teng CM. NPRL-Z-1, as a new topoisomerase II poison, induces cell apoptosis and ROS generation in human renal carcinoma cells. PLoS One. 2014; 9(11): e112220.
11. Chen MC, Pan SL, Liou JP, and Teng CM. Development of natural-based microtubule-interfering agents for cancer treatment. (preparing and submitting)
12. Chen CH, Chen MC, Wang JC, Liou JP, Pan SL, and Teng CM. The novel HDAC inhibitor, MPT0G028, induces cell death via regulation of b-catenin in human colon cancer HCT116 cells. (preparing and submitting)
13. Chen MC, Zhou B, Zhang K, Yuan YC, Un F, Hu S, Chou CM, Chen CH, Wu J, Wang Y, Liu X, Smith L, Warden CD, Liu Z, Li H, Su L, Malkas LH, Chung YM, Hu MC, Yen Y. The Novel Ribonucleotide Reductase Inhibitor COH29 Inhibits DNA Repair In Vitro. Mol Pharmacol. 2015 Mar 26. pii: mol.114.094987.